H3K27me3 and H2A.Z prime cold regulated genes, and their remodelling governs plant cold response
This study reveals that in Arabidopsis, cold-regulated genes are primed by high levels of H2A.Z and H3K27me3, where REF6-mediated H3K27me3 reduction and H2A.Z remodeling act as critical switches to modulate RNA polymerase II activity and drive the transcriptional response to cold stress.